Small leucine-rich proteoglycans in the aging skeleton
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Small leucine-rich proteoglycans in the aging skeleton. / Young, M F; Bi, Y; Ameye, L; Xu, T; Wadhwa, S; Heegaard, Anne-Marie; Kilts, T; Chen, X D.
In: Journal of Musculoskeletal and Neuronal Interactions, Vol. 6, No. 4, 2006, p. 364-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Small leucine-rich proteoglycans in the aging skeleton
AU - Young, M F
AU - Bi, Y
AU - Ameye, L
AU - Xu, T
AU - Wadhwa, S
AU - Heegaard, Anne-Marie
AU - Kilts, T
AU - Chen, X D
PY - 2006
Y1 - 2006
N2 - Small Leucine-Rich Proteoglyans (SLRPs) are major skeletal extracellular matrix (ECM) components that comprise a family of 13 members containing repeats of a leucine-rich motif. To examine SLRP function, we generated mice deficient in one or more member and analyzed them at the tissue, cell and molecular levels. This review outlines the novel research findings uncovered using these new animal models.
AB - Small Leucine-Rich Proteoglyans (SLRPs) are major skeletal extracellular matrix (ECM) components that comprise a family of 13 members containing repeats of a leucine-rich motif. To examine SLRP function, we generated mice deficient in one or more member and analyzed them at the tissue, cell and molecular levels. This review outlines the novel research findings uncovered using these new animal models.
KW - Aging
KW - Amino Acid Motifs
KW - Animals
KW - Biglycan
KW - Bone and Bones
KW - Coculture Techniques
KW - Decorin
KW - Extracellular Matrix
KW - Extracellular Matrix Proteins
KW - Mice
KW - Mice, Knockout
KW - Models, Animal
KW - Osteoblasts
KW - Osteoclasts
KW - Osteogenesis
KW - Physical Conditioning, Animal
KW - Proteoglycans
M3 - Journal article
C2 - 17185826
VL - 6
SP - 364
EP - 365
JO - Journal of Musculoskeletal Neuronal Interactions
JF - Journal of Musculoskeletal Neuronal Interactions
SN - 1108-7161
IS - 4
ER -
ID: 38426169