Relative bioavailability in man of noscapine administered in lozenges and mixture
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Relative bioavailability in man of noscapine administered in lozenges and mixture. / Jensen, L.N.; Christrup, Lona Louring; Jacobsen, L.; Bonde, J.; Bundgaard, H.
In: Acta Pharmaceutica Nordica, Vol. 4, No. 4, 01.01.1992, p. 309-312.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Relative bioavailability in man of noscapine administered in lozenges and mixture
AU - Jensen, L.N.
AU - Christrup, Lona Louring
AU - Jacobsen, L.
AU - Bonde, J.
AU - Bundgaard, H.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture.
AB - The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture.
UR - http://www.scopus.com/inward/record.url?scp=0027051811&partnerID=8YFLogxK
M3 - Journal article
AN - SCOPUS:0027051811
VL - 4
SP - 309
EP - 312
JO - Acta Pharmaceutica Nordica
JF - Acta Pharmaceutica Nordica
SN - 1100-1801
IS - 4
ER -
ID: 46100967