Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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α-Glucosidase inhibitory activity of plant extracts from the Danish Medicinal Plant Biobank
Madsen, A. T., Soelberg, Jens & Stærk, Dan, 8 Jun 2021. 1 p.Research output: Contribution to conference › Poster › Research
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α-Glucosidase inhibitors from Phyllanthus amarus and Phyllanthus urinaria
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity
Trinh, T. D. B., Quach, T. T. T., Bui, D. N., Stærk, Dan, Nguyen, L. D. & Jäger, A. K., 2017, In: Fitoterapia. 118, p. 126-131Research output: Contribution to journal › Journal article › Research › peer-review
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Vejledning til laboratorieøvelser i 'Organisk Kemi for Biovidenskab'
Stærk, Dan, 2012, Institut for Grundvidenskab og Miljø, Københavns Universitet. 74 p.Research output: Book/Report › Compendium/lecture notes › Education
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Unraveling the complexity of complex mixtures by combining high-resolution pharmacological, analytical and spectroscopic techniques: Antidiabetic constituents in Chinese medicinal plants
Zhao, Yong, Kongstad, Kenneth Thermann, Liu, Y., He, C. & Stærk, Dan, 2019, In: Faraday Discussions. 218, p. 202-218Research output: Contribution to journal › Journal article › Research › peer-review
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Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum
Frandsen, R. J. N., Schütt, C. W. H., Lund, B. L. W., Stærk, Dan, Nielsen, J., Olsson, S. & Giese, H., 2011, In: Journal of Biological Chemistry. 286, 12, p. 10419-10428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude extract of Radix Scutellariae
Tahtah, Y., Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N., Jønsson, L. H., Jäger, A. K., Qinglei, S. & Stærk, Dan, 2015, In: Journal of Chromatography A. 1408, p. 125-132 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii
Pateraki, Irini, Andersen-Ranberg, Johan, Jensen, N. B., Wubshet, S. G., Heskes, A. M., Forman, Victor, Hallström, B., Hamberger, B., Motawie, Mohammed Saddik, Olsen, C. E., Stærk, Dan, Hansen, J., Møller, Birger Lindberg & Hamberger, B. R., 2017, In: eLife. 6, 28 p., e23001.Research output: Contribution to journal › Journal article › Research › peer-review
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The α-glucosidase and PTP1B inhibitory effect of 45 medicinal plants extracts
Liu, B., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The causal mutation leading to sweetness in modern white lupin cultivars
Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.Research output: Contribution to journal › Journal article › Research › peer-review
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The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed
Ziegler, H. L., Hansen, Harald S., Stærk, Dan, Christensen, Søren Brøgger, Hägerstrand, H. & Jaroszewski, J. W., 2004, In: Antimicrobial Agents and Chemotherapy. 48, p. 4067-4071Research output: Contribution to journal › Journal article › Research › peer-review
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Terpenoids of Salvia hydrangea: two new, rearranged 20-norabietanes and the effect of oleanolic acid on erythrocyte membrane
Sairafianpour, M., Bahreininejad, B., Witt, M., Ziegler, H. L., Jaroszewski, J. W. & Stærk, Dan, 2003, In: Planta Medica. 69, p. 846-850Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance analysis with high-resolution radical scavenging profiles - bioactive secondary metabolites from the endophytic fungus Penicillium namyslowskii
Wubshet, S. G., Nyberg, N., Tejesvi, M. V., Pirttilä, A. M., Kajula, M., Mattila, S. & Stærk, Dan, 2013, In: Journal of Chromatography A. 1302, p. 34-39Research output: Contribution to journal › Journal article › Research › peer-review
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Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species
Sprogøe, K., Stærk, Dan, Jäger, A. K., Adsersen, A., Hansen, S. H., Witt, M., Landbo, A. R., Meyer, A. S. & Jaroszewski, J. W., 2007, In: Journal of Natural Products. 70, 9, p. 1472-1477Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of C-glucosylated octaketide anthraquinones in Nicotiana benthamiana using a multispecies-based biosynthetic pathway
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nafisi, M., Stærk, Dan, Okkels, F. T., Mortensen, U. H., Møller, Birger Lindberg, Frandsen, R. J. N. & Kannangara, R. M., 2017, In: ChemBioChem. 18, 19, p. 1893-1897 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Hansen, A. N., Bendiksen, C. D., Sylvest, L., Friis, T., Stærk, Dan, Jørgensen, Flemming Steen, Olsen, Christian Adam & Houen, G., 2012, In: P L o S One. 7, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography
Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure elucidation and absolute configuration determination of nortriterpenoids from Picramnia glazioviana
Gimenes, L., Luna-Dulcey, L., Batista Junior, J. M., dos Santos Junior, F. M., Popolin, C. P., Cominetti, M. R., Fernandes, J. B. & Stærk, Dan, 2020, In: Journal of Natural Products. 83, p. 1859-1876Research output: Contribution to journal › Journal article › Research › peer-review
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Structural analysis of complex saponins of Balanites aegyptiaca by 800 MHz 1H NMR spectroscopy
Stærk, Dan, Chapagain, B. P., lindin, T., Wiesman, Z. & Jaroszewski, J. W., 2006, In: Magnetic Resonance in Chemistry. 44, p. 923-928Research output: Contribution to journal › Journal article › Research › peer-review
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Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spektroskopi – Strukturopklaring vha NMR og IR: Kompendium med forelæsningsslides, tabeller og opgavesamling til en undervisningsdag i spektroskopi ved Institut for Lægemiddeldesign og Farmakologi på Det Sundhedsvidenskabelige Fakultet, Københavns Universitet.
Stærk, Dan, 2016, 74 p.Research output: Book/Report › Compendium/lecture notes › Education
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Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS
Kongstad, Kenneth Thermann, Papathanasiou, T., Springborg, A., Lund, Trine Meldgaard, Werner, M. U. & Stærk, Dan, 2019, In: Bioanalysis. 11, 03, p. 165-173Research output: Contribution to journal › Journal article › Research › peer-review
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Serrulatane diterpenoids with unusual side chain modifications from root bark of Eremophila longifolia
Rasmussen, L. F., Anton, Jennifer, Kjaerulff, Louise, Zhao, Yong, Semple, S. J., Ndi, C., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 203, 14 p., 113408.Research output: Contribution to journal › Journal article › Research › peer-review
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Serrulatane diterpenoids from the leaves of Eremophila glabra and their potential as antihyperglycemic drug leads
Petersen, M. J., Liang, Chao, Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 196, 11 p., 113072.Research output: Contribution to journal › Journal article › Research › peer-review
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Semi-synthesis of novel thebaine derivatives with low cytotoxicity and their antibacterial and antihemolytic properties
Hasanpour, Z., Salehi, P., Aliahmadi, A., Hoseinpour, M., Behboodi, H., Stærk, Dan & Bararjanian, M., 2023, In: Medicinal Chemistry Research. 32, p. 1713–1725Research output: Contribution to journal › Journal article › Research › peer-review
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Semi-synthesis of novel buprenorphine derivatives and their anti-nociceptive properties and dependency potential
Hasanpour, Z., Salehi, P., Bunch, Lennart, Khoramjouy, M., Bararjanian, M., Stærk, Dan & Faizi, M., 2021, In: Canadian Journal of Chemistry. 99, 11, p. 910-919Research output: Contribution to journal › Journal article › Research › peer-review
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Selagoline, a new alkaloid from Huperzia selago
Stærk, Dan, Larsen, J., Larsen, L. A., Olafsdottir, E. S., Witt, M. & Jaroszewski, J. W., 2004, In: Natural Product Research. 18, p. 197-203Research output: Contribution to journal › Journal article › Research › peer-review
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Secondary metabolite comparison of the species within the Heterobasidion annosum s.l. complex
Hansson, D., Wubshet, S. G., Olson, Å., Karlsson, M., Stærk, Dan & Broberg, A., 2014, In: Phytochemistry. 108, p. 243-251 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening selected Vietnamese plants used to treat diabetes for PTP1B inhibitory activity
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 2016, In: Journal of Ethnopharmacology. 186, p. 189-195 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock
Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.Research output: Contribution to journal › Journal article › Research › peer-review
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Recreational drug use at a major music festival: trend analysis of anonymised pooled urine
Hoegberg, L., Christiansen, C., Søe, J. L., Telving, R., Andreasen, M. F., Stærk, Dan, Christrup, Lona Louring & Kongstad, Kenneth Thermann, 2018, In: Clinical Toxicology. 56, p. 245-255 1360496.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica
Lambert, M., Stærk, Dan, Hansen, S. H., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Journal of Natural Products. 68, p. 1500-1509Research output: Contribution to journal › Journal article › Research › peer-review
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Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude root bark of Morus alba L.
Zhao, Yong, Kongstad, Kenneth Thermann, Jäger, A. K., Nielsen, J. & Stærk, Dan, 2018, In: Journal of Chromatography A. 1556, p. 55-63Research output: Contribution to journal › Journal article › Research › peer-review
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Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics
Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
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Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study
Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In: Journal of Natural Products. 74, 10, p. 2206-2215Research output: Contribution to journal › Journal article › Research › peer-review
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Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum
Sørensen, J. L., Hansen, F. T., Søndergaard, T. E., Stærk, Dan, Lee, T. V., Wimmer, R., Klitgaard, L. G., Purup, S., Giese, H. & Frandsen, R. J. N., 2012, In: Environmental Microbiology. 14, 5, p. 1159-1170 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential of Sorbus berry extracts for management of type 2 diabetes: metabolomics investigation of 1H NMR spectra, α-amylase and α-glucosidase inhibitory activities, and in vivo anti-hyperglycaemic activity of S. norvegica
Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2019, In: Journal of Ethnopharmacology. 242, 10 p., 112061.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential of Polygonum cuspidatum root as an antidiabetic food: Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic constituents
Zhao, Yong, Chen, M. X., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, 2017, In: Journal of Agricultural and Food Chemistry. 65, p. 4421-4427Research output: Contribution to journal › Journal article › Research › peer-review
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Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives
Liang, Chao, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Journal of Functional Foods. 64, 10 p., 103623.Research output: Contribution to journal › Journal article › Research › peer-review
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Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens
Ziegler, H. L., Jensen, T. H., Christensen, J., Stærk, Dan, Hägerstrand, H., Sittie, A. A., Olsen, C. E., Staalsø, Trine, Ekpe, P. & Jaroszewski, J. W., 2002, In: Planta Medica. 68, p. 547-549 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts
Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plantemetabolomer in action
Schmidt, B., Stærk, Dan, Bro, Rasmus & Jaroszewski, J. W., 2006, In: Lægemiddelforskning. 2006, p. 4-5 2 p.Research output: Contribution to journal › Journal article › Research
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Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora:
Kesting, J. R., Tolderlund, I., Pedersen, A. F., Witt, M., Jaroszewski, J. W. & Stærk, Dan, 2009, In: Journal of Natural Products. 72, 2, p. 312-315 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Picraviane A and B: Nortriterpenes with limonoid-like skeletons containing a heptanolide E-ring system from Picramnia glazioviana
Gimenes, L., Batista Junior, J. M., dos Santos Junior, F. M., Souza, M. D. S., Luna-Dulcey, L., Ellena, J., Cominetti, M. R., da Silva, M. F. D. G. F., Vieira, P. C., Fernandes, J. B. & Stærk, Dan, 2019, In: Phytochemistry. 163, p. 38-45Research output: Contribution to journal › Journal article › Research › peer-review
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Phytochemical investigation of Eremophila spp.
Bredahl, E. K., Ergin, Y., Kjaerulff, Louise & Stærk, Dan, 2021, p. 1.Research output: Contribution to conference › Poster › Research
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Phenanthroindolizidine alkaloids from Vincetoxicum pumilum
Stærk, Dan, Nezhad, K. B., Asili, J., Emami, S. A., Ahi, A., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Biochemical Systematics and Ecology. 33, p. 957-960Research output: Contribution to journal › Journal article › Research › peer-review
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Peptides from chicken processing by-product inhibit DPP-IV and promote cellular glucose uptake: potential ingredients for T2D management
Lima, R. D. C. L., Berg, R. S., Rønning, S. B., Afseth, N. K., Knutsen, S. H., Stærk, Dan & Wubshet, S. G., 2019, In: Food & Function. 10, p. 1619-1628Research output: Contribution to journal › Journal article › Research › peer-review
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PTP1B-inhibiting branched-chain fatty acid dimers from Eremophila oppositifolia subsp. angustifolia identified by high-resolution PTP1B inhibition profiling and HPLC-PDA-HRMS-SPE-NMR analysis
Pedersen, H. A., Ndi, C., Semple, S. J., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 7 Apr 2020, In: Journal of Natural Products. 83, p. 1598-1610Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidation and cyclization of Casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L
Luo, Dan, Callari, R., Hamberger, B., Wubshet, S. G., Nielsen, M. T., Andersen-Ranberg, Johan, Hallström, B. M., Cozzi, F., Heider, H., Møller, Birger Lindberg, Stærk, Dan & Hamberger, B. R., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. E5082-E5089 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810Research output: Contribution to journal › Journal article › Research › peer-review
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Orthogonal reversed-phase C18 and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata
Zhao, Yong, Li, T., Kjaerulff, Louise, Venter, H., Coriani, S., Møller, Birger Lindberg, Semple, S. & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 12, p. 2638-2650Research output: Contribution to journal › Journal article › Research › peer-review
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On the biosynthetic origin of carminic acid
Rasmussen, S. A., Kongstad, Kenneth Thermann, Khorsand-Jamal, P., Kannangara, R. M., Nafisi, M., Van Dam, A., Bennedsen, M., Madsen, B., Okkels, F. T., Gotfredsen, C. H., Stærk, Dan, Thrane, U., Mortensen, U. H., Larsen, T. O. & Frandsen, R. J. N., 2018, In: Insect Biochemistry and Molecular Biology. 96, p. 51-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Når filmens fiktion bliver virkelighed
Stærk, Dan, Lambert, M., Sairafianpour, M., Clarkson, C. & Jaroszewski, J. W., 2004, In: Lægemiddelforskning. p. 12-13Research output: Contribution to journal › Journal article › Communication
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Noter til M25-1 spektroskopi
Stærk, Dan & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi. 49 p.Research output: Book/Report › Compendium/lecture notes › Education
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Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Poster › Research
- Published
Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009. 1 p.Research output: Contribution to conference › Poster › Research
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New resistance-correlated saponins from the insect-resistant crucifer Barbarea vulgaris
Nielsen, Nikoline Juul, Nielsen, J. & Stærk, Dan, 2010, In: Journal of Agricultural and Food Chemistry. 58, 9, p. 5509-5514 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New dammarane and malabaricane triterpenes from Caloncoba echinata
Ziegler, H. L., Stærk, Dan, Christensen, J., Olsen, C. E., Sittie, A. A. & Jaroszewski, J. W., 2002, In: Journal of Natural Products. 65, p. 1764-1768Research output: Contribution to journal › Journal article › Research › peer-review
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New bisbenzylisoquinoline alkaloid from Laureliopsis philippiana
Stærk, Dan, Thi, L. P., Rasmussen, H. B., Guzmán, A. & Mølgaard, Per, 2009, In: Fitoterapia. 80, 2, p. 112-114 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species
Gericke, Oliver, Hansen, N. L., Pedersen, G. B., Kjaerulff, Louise, Luo, Dan, Stærk, Dan, Møller, Birger Lindberg, Pateraki, Irini & Heskes, A., 2020, In: B M C Plant Biology. 20, 15 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila
Gericke, Oliver, Fowler, R., Heskes, A., Bayly, M., Semple, S., Ndi, C. P., Stærk, Dan, Loland, Claus Juul, Murphy, D. J., Buirchell, B. & Møller, Birger Lindberg, 2021, In: Plant Journal. 108, 2, p. 555-578Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NMR-spectroscopic studies, and pharmacological evaluation of alkaloids from some medicinal plants
Stærk, Dan, 2000, Royal Danish school of Pharmacy.Research output: Book/Report › Ph.D. thesis › Research
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NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. & Stærk, Dan, 2015. 1 p.Research output: Contribution to conference › Poster › Research
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NMR-based metabolomics and hyphenated NMR techniques – a perfect match in natural products research
Vinther, J. M., Wubshet, S. G. & Stærk, Dan, Aug 2015, Ethnopharmacology - a Reader. Heinrich, M. & Jäger, A. K. (eds.). Chichester: Wiley, p. 63-74Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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NMR for gymnasieelever: forelæsningsslides, tabeller og opgavesamling til en NMR undervisningssession for gymnasieelever
Stærk, Dan, 2010, Institut for Grundvidenskab og Miljø, Københavns Universitet. 39 p.Research output: Book/Report › Compendium/lecture notes › Education
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Multivariate analysis of integrated and full-resolution 1H-NMR spectral data from complex pharmaceutical preparations: St. John's wort
Rasmussen, B., Cloarec, O., Tang, H., Stærk, Dan & Jaroszewski, J. W., 2006, In: Planta Medica. 72, p. 556-563Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular phylogenetics as a predictive tool in plant-based drug discovery in the genus Euphorbia L.
Ernst, M., Saslis Lagoudakis, H., Grace, O. M., Nilsson, N., Simonsen, H. T., Horn, J. W., Stærk, Dan & Rønsted, Nina, 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Moderne naturstofkemi: effektiv analyse af naturens stofbiblioteker
Stærk, Dan, Lemmich, E., Franzyk, Henrik, Lemmich, J. & Jaroszewski, J. W., 2000, In: Lægemiddelforskning. p. 6-7Research output: Contribution to journal › Journal article › Communication
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Microwave-assisted ring-opening of activated aziridines with resin-bound amines
Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines
Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769Research output: Contribution to journal › Journal article › Research › peer-review
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Magnetic ligand fishing as a targeting tool for HPLC-HRMS-SPE-NMR: α-glucosidase inhibitory ligands and alkylresorcinol glycosides from Eugenia catharinae.
Wubshet, S. G., Brighente, I. M. C., Moaddel, R. & Stærk, Dan, 2015, In: Journal of Natural Products. 78, 11, p. 2657-2665 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lægemidler fra naturstoffer: fortid eller fremtid?
Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6Research output: Contribution to journal › Journal article › Communication
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Ligand-fishing and bioactivity-correlated metabolomics for accelerated discovery of antidiabetic drug leads
Nyberg, N. T., Wubshet, S. G., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones
Sairafianpour, M., Christensen, J., Stærk, Dan, Budnik, B. A., Kharazmi, A., Bagherzadeh, K. & Jaroszewski, J. W., 2001, In: Journal of Natural Products. 64, 11, p. 1398-1403 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmanicidal, antiplasmodial and cytotoxic activity of indole alkaloids from Corynanthe pachyceras
Stærk, Dan, Lemmich, E., Christensen, J., Kharazmi, A., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Planta Medica. 66, p. 531-536Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica
Sairafianpour, M., Kayser, O., Christensen, J., Asfa, M., Witt, M., Stærk, Dan & Jaroszewski, J. W., 2003, In: Journal of Natural Products. 65, p. 1754-1768Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Labdanes and isopimaranes from Platycladus orientalis and their effects on erythrocyte membrane and on Plasmodium falciparum growth in the erythrocyte host cells
Asili, J., Lambert, M., Ziegler, H. L., Stærk, Dan, Sairafianpour, M., Witt, M., Asghari, G., Ibrahimi, I. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, p. 631-637Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jagten på bioaktive naturstoffer: Sammenkoblet HPLC-PDA-HRMS-SPE-NMR til hurtig identifikation af bioaktive naturstoffer i komplekse blandinger
Stærk, Dan, 2021, In: Dansk Kemi. 102, 4, p. 40-44Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Stanstrup, Jan, Rusch, A., Agnolet, S., Rasmussen, H. B., Mølgaard, Per, Van Staden, J., Stafford, G. I. & Stærk, Dan, 2010, In: Biochemical Systematics and Ecology. 38, 3, p. 346-348 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation, structure elucidation and PTP1B inhibitory activity of serrulatane diterpenoids from the roots of Myoporum insulare
Kjaerulff, Louise, Jensen, A. B. J., Ndi, C., Semple, S. J., Møller, Birger Lindberg & Stærk, Dan, 2020, In: Phytochemistry Letters. 39, p. 49-56Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach
Stærk, Dan, Skole, B., Jørgensen, Flemming Steen, Budnik, B. A., Ekpe, P. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, 5, p. 799-805 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and structure elucidation of serrulatane diterpenoids from the roots of Eremophila longifolia
Rasmussen, L. F., Anton, J., Kjaerulff, Louise & Stærk, Dan, 2021, p. 1.Research output: Contribution to conference › Poster › Research
- Published
Isolation and structure elucidation of cyclopeptide alkaloids from Ziziphus nummularia and Ziziphus spina-christi by HPLC-DAD-MS and HPLC-PDA-HRMS-SPE-NMR
Tuenter, E., Foubert, K., Stærk, Dan, Apers, S. & Pieters, L., 2017, In: Phytochemistry. 138, p. 163-169Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata
Bredahl, E. K., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry Letters. 47, p. 156-163Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro
Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites
Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of medicinal plants from Madagascar against DPP-IV linked to type 2 diabetes
Beidokhti, M. N., Lobbens, E. S. B., Rasoavaivo, P., Jäger, A. K. & Stærk, Dan, Mar 2018, In: South African Journal of Botany. 115, p. 113-119Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of antidiabetic potential of Phyllanthus niruri L. using assays for α-glucosidase, muscle glucose transport, liver glucose production, and adipogenesis
Beidokhti, M. N., Andersen, M. V., Eid, H. M., Villavicencio, M. L. S., Stærk, Dan, Haddad, P. S. & Jäger, A. K., 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 869-874Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol
Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intact penetratin metabolite permeates across Caco-2 monolayers
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.Research output: Contribution to conference › Poster › Research
- Published
Insects as sources for sustainable peptide drugs against type 2 diabetes
Didriksen, A. H., Petersen, M. J. & Stærk, Dan, 8 Jun 2021. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Inhibitory potential of 40 medicinal plant extracts from Madagascar against enzymes linked to type 2 diabetes
Beidokhti, M. N., Lobbens, E. S., Rasoavaivo, P., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
Inhibition of α-glucosidase activity by selected edible seaweeds and fucoxanthin
Zaharudin, N. B., Stærk, Dan & Dragsted, Lars Ove, 2019, In: Food Chemistry. 270, p. 481-486 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768Research output: Contribution to journal › Journal article › Research
- Published
In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells
Stærk, Dan, Lykkeberg, A. K., Christensen, J., Budnik, B. A., Abe, F. & Jaroszewski, J. W., 2002, In: Journal of Natural Products. 65, p. 1299-1302Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved solid-phase synthesis and study of arylopeptoids with conformation-directing side chains
Hjelmgaard, T., Faure, S., De Santis, E., Stærk, Dan, Alexander, B. D., Edwards, A. A., Taillefumier, C. & Nielsen, J., 2012, In: Tetrahedron. 68, 23, p. 4444-4454 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immobilized α-amylase magnetic beads for ligand fishing: Proof of concept and identification of α-amylase inhibitors in Ginkgo biloba
Petersen, M. J., Lima, R. D. C. L., Kjaerulff, Louise & Stærk, Dan, 2019, In: Phytochemistry. 164, p. 94-101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Schmidt, J. S., Daykin, C. A. & Stærk, Dan, 2012. 1 p.Research output: Contribution to conference › Poster › Research
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
Research output: Contribution to journal › Journal article › Research › peer-review
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