Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- 2016
- Published
- Published
High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)
Lana e Silva, E., Felipe Revoredo Lobo, J., Vinther, J. M., Moreira Borges, R. & Stærk, Dan, 2016, In: Molecules. 21, 6, 19 p., 782.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of PTP1B and α-glucosidase inhibitory serrulatanes from Eremophila spp. by combined use of dual high-resolution PTP1B and α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR
Wubshet, S. G., Tahtah, Y., Heskes, A. M., Kongstad, Kenneth Thermann, Pateraki, Irini, Hamberger, B. R., Møller, Birger Lindberg & Stærk, Dan, 2016, In: Journal of Natural Products. 79, 4, p. 1063-1072 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular phylogenetics as a predictive tool in plant-based drug discovery in the genus Euphorbia L.
Ernst, M., Saslis Lagoudakis, H., Grace, O. M., Nilsson, N., Simonsen, H. T., Horn, J. W., Stærk, Dan & Rønsted, Nina, 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oxidation and cyclization of Casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L
Luo, Dan, Callari, R., Hamberger, B., Wubshet, S. G., Nielsen, M. T., Andersen-Ranberg, Johan, Hallström, B. M., Cozzi, F., Heider, H., Møller, Birger Lindberg, Stærk, Dan & Hamberger, B. R., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. E5082-E5089 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 2016, In: Journal of Ethnopharmacology. 186, p. 189-195 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spektroskopi – Strukturopklaring vha NMR og IR: Kompendium med forelæsningsslides, tabeller og opgavesamling til en undervisningsdag i spektroskopi ved Institut for Lægemiddeldesign og Farmakologi på Det Sundhedsvidenskabelige Fakultet, Københavns Universitet.
Stærk, Dan, 2016, 74 p.Research output: Book/Report › Compendium/lecture notes › Education
- 2015
- Published
High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Clausena excavata
Liu, Y., Stærk, Dan, Nyberg, N. & Jager, A. K., Nov 2015, In: Planta Medica. 81, 16, p. 1432-1432Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N. T., Sun, Q., Jager, A. K. & Stærk, Dan, Nov 2015, In: Planta Medica. 81, 16, p. 1437-1437Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-resolution assays combined with HPLC for identification of antidiabetic constituents in Vietnamese plants
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata
Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. K. & Stærk, Dan, 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
Inhibitory potential of 40 medicinal plant extracts from Madagascar against enzymes linked to type 2 diabetes
Beidokhti, M. N., Lobbens, E. S., Rasoavaivo, P., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
NMR-based metabolomics and hyphenated NMR techniques – a perfect match in natural products research
Vinther, J. M., Wubshet, S. G. & Stærk, Dan, Aug 2015, Ethnopharmacology - a Reader. Heinrich, M. & Jäger, A. K. (eds.). Chichester: Wiley, p. 63-74Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts
Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: accelerated identification of bioactive constituents in food and medicinal plants
Stærk, Dan, 2015.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae)
Wubshet, S. G., Moresco, H. H., Tahtah, Y., Brighente, I. M. C. & Stærk, Dan, 2015, In: Phytochemistry. 116, p. 246-252 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite
Liu, Y., Stærk, Dan, Nielsen, M. N., Nyberg, N. & Jäger, A. K., 2015, In: Phytochemistry. 119, p. 62-69 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata
Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A., 2015.Research output: Contribution to conference › Poster › Research
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. & Stærk, Dan, 2015.Research output: Contribution to conference › Poster › Research
- Published
Identification of Fungal Plasma Membrane H+-ATPase Inhibitors in Lecaniodiscus cupanioides by HPLC-HRMS-SPE-NMR
Straadt, I. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2015.Research output: Contribution to conference › Poster › Research
- Published
Intact penetratin metabolite permeates across Caco-2 monolayers
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.Research output: Contribution to conference › Poster › Research
- Published
Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites
Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Magnetic ligand fishing as a targeting tool for HPLC-HRMS-SPE-NMR: α-glucosidase inhibitory ligands and alkylresorcinol glycosides from Eugenia catharinae.
Wubshet, S. G., Brighente, I. M. C., Moaddel, R. & Stærk, Dan, 2015, In: Journal of Natural Products. 78, 11, p. 2657-2665 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. & Stærk, Dan, 2015. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude extract of Radix Scutellariae
Tahtah, Y., Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N., Jønsson, L. H., Jäger, A. K., Qinglei, S. & Stærk, Dan, 2015, In: Journal of Chromatography A. 1408, p. 125-132 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
African plants for inhibition of necrotic enzymes from snake venom
Schmidt, M. M., Nielsen, L., Søgaard, S., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A. K., 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2
Devkota, K., Lohse, B., Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In: A C S Medicinal Chemistry Letters. 5, 4, p. 293-297Research output: Contribution to journal › Letter › Research › peer-review
- Published
Assessment of constituents in Allium by multivariate data analysis, high-resolution α-glucosidase inhibition assay and HPLC-SPE-NMR
Schmidt, J. S., Nyberg, N. & Stærk, Dan, 2014, In: Food Chemistry. 161, p. 192-198 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution Assays Combined with HPLC-HRMS-SPE-ttNMR for Identification of Antidiabetic Compounds in root of Scutellaria Baicalensis
Tahtah, Y., Jønsson, L. H., Nyberg, N., Jäger, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
High-resolution bacterial growth inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antibacterial constituents in Chinese plants used to treat snakebites
Liu, Y., Nielsen, M., Stærk, Dan & Jäger, A., 2014, In: Journal of Ethnopharmacology. 155, 2, p. 1276-1283 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution bioactivity profiling combined with hyphenated HPLC-SPE-NMR – Investigation of functional food and plants with antifungal constituents
Stærk, Dan, 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
High-resolution screening combined with HPLC–HRMS–SPE–NMR for identification of fungal plasma membrane H+-ATPase inhibitors from plants
Kongstad, Kenneth Thermann, Wubshet, S. G., Johannesen, A., Kjellerup, L., winther, A. L., Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 24, p. 5595-5602 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution α-amylase assay combined with high-performance liquid chromatography−solid-phase extraction−nuclear magnetic resonance spectroscopy for expedited identification of α-amylase inhibitors – proof of concept and α-amylase inhibitor in cinnamon.
Okutan, L., Kongstad, Kenneth Thermann, Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 47, p. 11465-11471 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa
Schmidt, M. M., Nielsen, L. H., Søgaard, S. V., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., van Staden, J. & Jäger, A., 2014, In: Journal of Ethnopharmacology. 157, p. 171-180 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Fungal H+-ATPase Inhibitors by Microfractionation and HPLC-HRMS-SPE-NMR
Wubshet, S. G., Kongstad, Kenneth Thermann, Johannesen, A., Nyberg, N., Jäger, A., Kjellerup, L., Vinther, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics
Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
Secondary metabolite comparison of the species within the Heterobasidion annosum s.l. complex
Hansson, D., Wubshet, S. G., Olson, Å., Karlsson, M., Stærk, Dan & Broberg, A., 2014, In: Phytochemistry. 108, p. 243-251 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Coupling HPLC-SPE-NMR with a microplate-based high-resolution antioxidant assay for efficient analysis of antioxidants in food – Validation and proof-of-concept study with caper buds
Wiese, S., Wubshet, S. G., Nielsen, J. & Stærk, Dan, 2013, In: Food Chemistry. 141, 4, p. 4010-4018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity-profiling of plant extracts
Grosso, C., Jäger, A. & Stærk, Dan, 2013, In: Phytochemical Analysis. 24, 2, p. 141-147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution screening combined with HPLC–HRMS–SPE–NMR for identification of potential health-promoting constituents in sea aster and searocket - New nordic food ingredients
Wubshet, S. G., Schmidt, J. S., Wiese, S. & Stærk, Dan, 2013, In: Journal of Agricultural and Food Chemistry. 61, 36, p. 8616-8623Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance analysis with high-resolution radical scavenging profiles - bioactive secondary metabolites from the endophytic fungus Penicillium namyslowskii
Wubshet, S. G., Nyberg, N., Tejesvi, M. V., Pirttilä, A. M., Kajula, M., Mattila, S. & Stærk, Dan, 2013, In: Journal of Chromatography A. 1302, p. 34-39Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-perfomance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay
Agnolet, S., Wiese, S., Verpoorte, R. & Stærk, Dan, 2012, In: Journal of Chromatography A. 1262, p. 130-137 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus × domestica Borkh.)
Schmidt, J. S., Lauridsen, M. B., Dragsted, Lars Ove, Nielsen, J. & Stærk, Dan, 2012, In: Food Chemistry. 135, 3, p. 1692-1699 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis
Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fremtidens funktionelle fødevarer - et vigtigt middel i kampen mod livsstilssygdomme
Stærk, Dan, 2012, Profil/Fødevarer & Sundhed. København: Københavns Universitet, Kommunikation, p. 18-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
High resolution antioxidant assay guided HPLC-HRMS-SPE-NMR analysis of Penicillium namyslowskii extract
Wubshet, S. G., Nyberg, N. & Stærk, Dan, 2012.Research output: Contribution to conference › Poster › Research
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Research output: Contribution to conference › Poster › Research
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4031
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Research output: Contribution to journal › Journal article › Research › peer-review
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2999
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
Research output: Contribution to journal › Journal article › Research › peer-review
Published