Trond Ulven

Trond Ulven

Professor

Member of:

    ORCID: 0000-0002-8135-1755

    Publication year:
    All
    76 - 100 out of 157Page size: 25
    1. 2013

    2. Discovery of a potent and selective free fatty acid receptor 1 agonist with low lipophilicity and high oral bioavailability

      Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schmidt, J., Hansen, S. V. F., Hudson, B. D., Zaibi, M., Markussen, S. B., Hagesaether, E., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 982-992 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Reevaluation of Fatty acid receptor 1 (FFAR1/GPR40) as drug target for the stimulation of insulin secretion in humans

      Wagner, R., Kaiser, G., Gerst, F., Ulven, Elisabeth Rexen, Due-Hansen, M. E., Grundmann, M., Machicao, F., Peter, A., Kostenis, E., Ulven, Trond, Fritsche, A., Häring, H. & Ullrich, S., 1 Feb 2013, In: Diabetes. 62, 6, p. 2106-2111 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs

      Hudson, B. D., Ulven, Trond & Milligan, G., 1 Jan 2013, In: Current Topics in Medicinal Chemistry. 13, 1, p. 14-25 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Continuous Flow Nucleophilic Aromatic Substitution with Dimethylamine Generated in Situ by Decomposition of DMF

      Petersen, T. P., Larsen, A. F., Ritzén, A. & Ulven, Trond, 2013, In: Journal of Organic Chemistry. 78, 8, p. 4190-4195 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Mucus can change the permeation rank order of drug candidates

      Hagesaether, E., Ulven, Elisabeth Rexen, Due-Hansen, M. E. & Ulven, Trond, 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 276-282 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Selective copper catalysed aromatic N-arylation in water

      Engel-Andreasen, J., Shimpukade, B. & Ulven, Trond, 2013, In: Green Chemistry. 15, 2, p. 336-340 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

      Hudson, B. D., Shimpukade, B., Mackenzie, A. E., Butcher, A. J., Pediani, J. D., Ulven, Elisabeth Rexen, Heathcote, H., Tobin, A. B., Ulven, Trond & Milligan, G., 2013, In: Molecular Pharmacology. 84, 5, p. 710-725 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2012
    10. Published

      Preparation of ortho-fluoro substituted compounds for the treatment of metabolic diseases.

      Ulven, Trond & Christiansen, E., 11 Oct 2012, Patent No. WO 2012/136221A1

      Research output: Patent

    11. Published

      Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors

      Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Antidiabetic enolic glucoside of phenylpyruvic acid.

      Joubert, E., Fey, S. J., Louw, J., Ulven, Trond & Tyagi, R., 12 Apr 2012, Patent No. WO 2012/045363A1

      Research output: Patent

    13. Published

      A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer

      Blättermann, S., Peters, L., Ottersbach, P. A., Bock, A., Konya, V., Weaver, C. D., Gonzalez, A., Schröder, R., Tyagi, R., Luschnig, P., Gäb, J., Hennen, S., Ulven, Trond, Pardo, L., Mohr, K., Gütschow, M., Heinemann, A. & Kostenis, E., 2012, In: Nature Chemical Biology. 8, 7, p. 631-638 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      A concise synthesis of the potent inflammatory mediator 5-oxo-ETE

      Tyagi, R., Shimpukade, B., Blättermann, S., Kostenis, E. & Ulven, Trond, 2012, In: MedChemComm. 3, p. 195-198 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

      Hudson, B. D., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Kostenis, E., Adams, D. R., Ulven, Trond & Milligan, G., 2012, In: F A S E B Journal. 26, 12, p. 4951-4965 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Discovery of a potent and selective GPR120 agonist

      Shimpukade, B., Hudson, B. D., Hovgaard, C. K., Milligan, G. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 9, p. 4511-4515 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3

      Hudson, B. D., Tikhonova, I. G., Pandey, S. K., Ulven, Trond & Milligan, G., 2012, In: Journal of Biological Chemistry. 287, 49, p. 41195-41209 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

      Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schröder, R., Hudson, B. D., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2012, In: Journal of Medicinal Chemistry. 55, 14, p. 6624-6628 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2

      Schröder, R., Xue, L., Konya, V., Martini, L., Kampitsch, N., Whistler, J. L., Ulven, Trond, Heinemann, A., Pettipher, R. & Kostenis, E., 2012, In: P L o S One. 7, 3, p. e33329

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets

      Ulven, Trond, 2012, In: Frontiers in Endocrinology. 3

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Tetrasubstituted phenanthrolines as highly potent, water-soluble, and selective g-quadruplex ligands

      Larsen, A. F., Nielsen, M. C. & Ulven, Trond, 2012, In: Chemistry: A European Journal. 18, 35, p. 10892-10902 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The oxygen-mediated synthesis of 1,3-butadiynes in continuous flow

      Petersen, T. P., Polyzos, A., O'Brien, M., Ulven, Trond, Baxendale, I. R. & Ley, S. V., 2012, In: ChemSusChem (Print). 5, 2, p. 274-277 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 2011
    24. Published

      Method of synthesizing a 5-oxo-conjugated fatty acid

      Ulven, Trond & Tyagi, R., 27 Oct 2011, Patent No. WO 2011/131619 A1

      Research output: Patent

    25. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

      Schmidt, J., Smith, N. J., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Hudson, B. D., Ward, R. J., Drewke, C., Milligan, G., Kostenis, E. & Ulven, Trond, 10 Jan 2011, In: Journal of Biological Chemistry. 286, 12, p. 10628-10640 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Conjugated Linoleic Acids Mediate Insulin Release through Islet G Protein-coupled Receptor FFA1/GPR40

      Schmidt, J., Liebscher, K., Merten, N., Grundmann, M., Mielenz, M., Sauerwein, H., Ulven, Elisabeth Rexen, Due-Hansen, M. E., Ulven, Trond, Ullrich, S., Gomeza, J., Drewke, C. & Kostenis, E., 2011, In: Journal of Biological Chemistry. 286, 14, p. 11890-11894 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Efficient Synthesis of 4,7-Diamino Substituted 1,10-Phenanthroline-2,9-dicarboxamides

      Larsen, A. F. & Ulven, Trond, 2011, In: Organic Letters. 13, 13, p. 3546-3548 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Extracellular loop 2 of the free Fatty Acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator

      Smith, N. J., Ward, R. J., Stoddart, L. A., Hudson, B. D., Kostenis, E., Ulven, Trond, Morris, J. C., Tränkle, C., Tikhonova, I. G., Adams, D. R. & Milligan, G., 2011, In: Molecular Pharmacology. 80, 1, p. 163-173 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    Previous 1 2 3 4 5 6 7 Next

    ID: 187375453