Uffe Kristiansen
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2024
- Published
Long-term immune cell profiling in stroke patients with or without infections
Sørensen, N. V., Hasseldam, Henrik, Johansen, F. F., Kristiansen, Uffe, Overgaard, K., Iversen, Helle Klingenberg & Rasmussen, Rune Skovgaard, 2024, In: International Journal of Neuroscience. 134, 2, p. 197-205Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion
Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes
Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In: Scientific Reports. 10, 1, 12 p., 10078.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)
Leguizamon, Cesar Ramon Romero, Elnagar, M., Kristiansen, Uffe & Kohlmeier, Kristi Anne, 6 Feb 2019, In: Scientific Reports. p. 1 - 11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice
von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Anticonvulsive evaluation of THIP in the murine pentylenetetrazole kindling model: lack of anticonvulsive effect of THIP despite functional δ-subunit-containing GABAA receptors in dentate gyrus granule cells
Simonsen, C., Boddum, K., von Schoubye, N. L., Kloppenburg, A., Sønderskov, K., Hansen, S. L. & Kristiansen, Uffe, Aug 2017, In: Pharmacology Research & Perspectives. 5, 4, 15 p., e00322.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Astrocytic GABA transporter activity modulates excitatory neurotransmission
Boddum, K., Jensen, T. P., Magloire, V., Kristiansen, Uffe, Rusakov, D. A., Pavlov, I. & Walker, M. C., 25 Nov 2016, In: Nature Communications. 7, 10 p., 13572.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors
Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uterine contraction induced by Ghanaian plants used to induce abortion
Larsen, B. H., Soelberg, Jens, Kristiansen, Uffe & Jäger, A. K., 2016, In: South African Journal of Botany. 106, p. 137-39 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology
Krall, J., Balle, T., Krogsgaard-Larsen, N., Sørensen, T. E., Krogsgaard-Larsen, Povl, Kristiansen, Uffe & Frølund, Bente, 2015, Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72. p. 201-27 27 p. (Advances in Pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2014
- Published
The GABAA Antagonist DPP-4-PIOL Selectively Antagonises Tonic over Phasic GABAergic Currents in Dentate Gyrus Granule Cells
Boddum, K., Frølund, Bente & Kristiansen, Uffe, 8 Aug 2014, In: Neurochemical Research. 39, 11, p. 2078–2084 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hippocampal P3-Like Auditory Event-Related Potentials are Disrupted in a Rat Model of Cholinergic Degeneration in Alzheimer's Disease: Reversal by Donepezil Treatment: Reversal by Donepezil Treatment
Laursen, B., Mørk, A., Kristiansen, Uffe & Bastlund, J. F., 2 Jul 2014, In: Journal of Alzheimer's Disease. 42, 4, p. 1179–1189 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats
Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration
Laursen, B., Mørk, A., Plath, N., Kristiansen, Uffe & Bastlund, J. F., 11 Nov 2013, In: Brain Research. 1543, p. 253-262Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors
Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, Uffe, Krogsgaard-Larsen, Povl, Bräuner, Hans, Ebert, B., Frølund, Bente, Cryan, J. F. & Jensen, Anders A., Oct 2013, In: British Journal of Pharmacology. 170, 4, p. 919-32 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leukocyte infiltration in experimental stroke
Grønberg, N. V., Johansen, F. F., Kristiansen, Uffe & Hasseldam, Henrik, 18 Sep 2013, In: Journal of Neuroinflammation. 10, 9 p., 115.Research output: Contribution to journal › Review › Research › peer-review
- Published
Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment
Kjærby, Celia, Bundgaard, C., Fejgin, K., Kristiansen, Uffe & Dalby, N. O., Sep 2013, In: Neuropharmacology. 72, p. 157-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholinergic degeneration is associated with increased plaque deposition and cognitive impairment in APPswe/PS1dE9 mice
Laursen, B., Mørk, A., Plath, N., Kristiansen, Uffe & Bastlund, J. F., 1 Mar 2013, In: Behavioural Brain Research. 240, 1, p. 146-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological evidence of functional inhibitory metabotrophic glutamate receptors on mouse arousal-related cholinergic laterodorsal tegmental neurons
Kohlmeier, Kristi Anne, Christensen, M. H., Kristensen, M. P. & Kristiansen, Uffe, 2013, In: Neuropharmacology. 66, p. 99-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as ¿-aminobutyric acidA receptor agonists
Petersen, J. G., Bergmann, R., Møller, H. A., Jørgensen, Charlotte Grube, Nielsen, Birgitte, Kehler, J., Frydenvang, Karla Andrea, Kristensen, Jesper Langgaard, Balle, T., Jensen, Anders A., Kristiansen, Uffe & Frølund, Bente, 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 993-1006Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan
Jeppesen, A. S., Kristiansen, Uffe, Soelberg, Jens & Jäger, A. K., 14 Jun 2012, In: Journal of Ethnopharmacology. 141, 3, p. 1077-1079 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?
Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder
Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In: Lægemiddelforskning. 2011, p. 23-25Research output: Contribution to journal › Journal article › Communication
ID: 985515
Most downloads
-
182
downloads
Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
181
downloads
Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
171
downloads
Astrocytic GABA transporter activity modulates excitatory neurotransmission
Research output: Contribution to journal › Journal article › Research › peer-review
Published