Uffe Kristiansen

Uffe Kristiansen

Associate Professor


  1. Published

    Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies

    Frølund, Bente, Kristiansen, Uffe, Krogsgaard-Larsen, Povl & Liljefors, T., 2008, Chemistry and molecular aspects of drug design and action. Rekka, E. A. & Kourounakis, P. N. (eds.). Boca Raton, Fl: CRC Press, p. 139-147

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  2. Published

    Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors

    Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Leukocyte infiltration in experimental stroke

    Grønberg, N. V., Johansen, F. F., Kristiansen, Uffe & Hasseldam, Henrik, 18 Sep 2013, In: Journal of Neuroinflammation. 10, 9 p., 115.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus

    Hansen, S. L., Nielsen, A. H., Knudsen, K. E., Artmann, A., Kristiansen, Uffe, Hansen, S. H., Hansen, Harald S. & Petersen, G., 2009, In: Neurochemistry International. 54, 3-4, p. 199-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?

    Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effects of GABAA receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions

    Hansen, S. L., Ebert, B., Fjalland, B. & Kristiansen, Uffe, 2001, In: British Journal of Pharmacology. 133, 4, p. 539-549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of acute injections of the ketone bodies in PTZ kindled mice

    Hansen, S. L., Riisberg, M., Nouri-Nejad, A., Skonberg, C., Kristiansen, Uffe & Hansen, Harald S., 2008.

    Research output: Contribution to conferencePosterResearch

  8. Published

    The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors

    Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, Uffe, Krogsgaard-Larsen, Povl, Bräuner, Hans, Ebert, B., Frølund, Bente, Cryan, J. F. & Jensen, Anders A., Oct 2013, In: British Journal of Pharmacology. 170, 4, p. 919-32 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Functional characterisation of the human alpha1 glycine receptor in a fluorescence-based membrane potential assay

    Jensen, Anders A. & Kristiansen, Uffe, 2004, In: Biochemical Pharmacology. 67, 9, p. 1789-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists

    Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In: Journal of Medicinal Chemistry. 50, 7, p. 1610-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan

    Jeppesen, A. S., Kristiansen, Uffe, Soelberg, Jens & Jäger, A. K., 14 Jun 2012, In: Journal of Ethnopharmacology. 141, 3, p. 1077-1079 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion

    Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder

    Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In: Lægemiddelforskning. 2011, p. 23-25

    Research output: Contribution to journalJournal articleCommunication

  14. Published

    Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment

    Kjærby, Celia, Bundgaard, C., Fejgin, K., Kristiansen, Uffe & Dalby, N. O., Sep 2013, In: Neuropharmacology. 72, p. 157-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats

    Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state

    Kohlmeier, Kristi Anne & Kristiansen, Uffe, 15 Dec 2010, In: Neuroscience. 171, 3, p. 812-29 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: Implications for control of behavioral state

    Kohlmeier, Kristi Anne & Kristiansen, Uffe, 2009, In: Journal of Neuroscience.

    Research output: Contribution to journalConference abstract in journalResearch

  18. Published

    Pharmacological evidence of functional inhibitory metabotrophic glutamate receptors on mouse arousal-related cholinergic laterodorsal tegmental neurons

    Kohlmeier, Kristi Anne, Christensen, M. H., Kristensen, M. P. & Kristiansen, Uffe, 2013, In: Neuropharmacology. 66, p. 99-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology

    Krall, J., Balle, T., Krogsgaard-Larsen, N., Sørensen, T. E., Krogsgaard-Larsen, Povl, Kristiansen, Uffe & Frølund, Bente, 2015, Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72. p. 201-27 27 p. (Advances in Pharmacology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Hydroxylated analogues of 5-aminovaleric acid as 4-aminobutyric acidB receptor antagonists: stereostructure-activity relationships

    Kristiansen, Uffe, bjl587, bjl587, Herdeis, C., Lund, Trine Meldgaard, Nielsen, Birgitte, Hansen, J. J., Falch, E., Hjeds, H. & Krogsgaard-Larsen, Povl, Mar 1992, In: Journal of Neurochemistry. 58, 3, p. 1150-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABA(A) receptor partial agonist, 4-PIOL

    Kristiansen, Uffe & Lambert, J. D. C., 1996, In: Neuropharmacology. 35, 9-10, p. 1181-1191 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Electrophysiological studies of the GABAA receptor ligand, 4‐PIOL, on cultured hippocampal neurones

    Kristiansen, Uffe, Lambert, J. D. C., Falch, E. & Krogsgaard-Larsen, Povl, Sep 1991, In: British Journal of Pharmacology. 104, 1, p. 85-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The low efficacy γ-aminobutyric acid type A agonist 5-(4- piperidyl)isoxazol-3-ol opens brief Cl- channels in embryonic rat olfactory bulb neurons

    Kristiansen, Uffe, Barker, J. L. & Serafini, R., 1995, In: Molecular Pharmacology. 48, 2, p. 268-279 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ligand Structural Specificity of GABAA Receptors in Guinea Pig Ileum

    Kristiansen, Uffe & Fjalland, B., May 1991, In: Pharmacology & Toxicology. 68, 5, p. 332-339 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Ligands for the GABAA receptor complex

    Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe & Ebert, B., 1 Jan 2001, Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology. CRC Press, p. 236-274 39 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

ID: 985515