Uffe Kristiansen
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
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Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies
Frølund, Bente, Kristiansen, Uffe, Krogsgaard-Larsen, Povl & Liljefors, T., 2008, Chemistry and molecular aspects of drug design and action. Rekka, E. A. & Kourounakis, P. N. (eds.). Boca Raton, Fl: CRC Press, p. 139-147Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors
Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukocyte infiltration in experimental stroke
Grønberg, N. V., Johansen, F. F., Kristiansen, Uffe & Hasseldam, Henrik, 18 Sep 2013, In: Journal of Neuroinflammation. 10, 9 p., 115.Research output: Contribution to journal › Review › Research › peer-review
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Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus
Hansen, S. L., Nielsen, A. H., Knudsen, K. E., Artmann, A., Kristiansen, Uffe, Hansen, S. H., Hansen, Harald S. & Petersen, G., 2009, In: Neurochemistry International. 54, 3-4, p. 199-204Research output: Contribution to journal › Journal article › Research › peer-review
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Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?
Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of GABAA receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions
Hansen, S. L., Ebert, B., Fjalland, B. & Kristiansen, Uffe, 2001, In: British Journal of Pharmacology. 133, 4, p. 539-549 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of acute injections of the ketone bodies in PTZ kindled mice
Hansen, S. L., Riisberg, M., Nouri-Nejad, A., Skonberg, C., Kristiansen, Uffe & Hansen, Harald S., 2008.Research output: Contribution to conference › Poster › Research
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The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors
Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, Uffe, Krogsgaard-Larsen, Povl, Bräuner, Hans, Ebert, B., Frølund, Bente, Cryan, J. F. & Jensen, Anders A., Oct 2013, In: British Journal of Pharmacology. 170, 4, p. 919-32 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional characterisation of the human alpha1 glycine receptor in a fluorescence-based membrane potential assay
Jensen, Anders A. & Kristiansen, Uffe, 2004, In: Biochemical Pharmacology. 67, 9, p. 1789-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing the pharmacophore of ginkgolides as glycine receptor antagonists
Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In: Journal of Medicinal Chemistry. 50, 7, p. 1610-1617Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-histamine effect of Rubia tibetica, used to treat anaphylaxis caused by tick bites in the Pamir Mountains, Afghanistan
Jeppesen, A. S., Kristiansen, Uffe, Soelberg, Jens & Jäger, A. K., 14 Jun 2012, In: Journal of Ethnopharmacology. 141, 3, p. 1077-1079 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion
Jørgensen, Anders, Thygesen, M. B., Kristiansen, Uffe & Poulsen, Henrik Enghusen, 2021, In: Scandinavian Journal of Clinical and Laboratory Investigation. 81, 7, p. 540-545Research output: Contribution to journal › Journal article › Research › peer-review
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Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder
Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In: Lægemiddelforskning. 2011, p. 23-25Research output: Contribution to journal › Journal article › Communication
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Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment
Kjærby, Celia, Bundgaard, C., Fejgin, K., Kristiansen, Uffe & Dalby, N. O., Sep 2013, In: Neuropharmacology. 72, p. 157-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats
Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state
Kohlmeier, Kristi Anne & Kristiansen, Uffe, 15 Dec 2010, In: Neuroscience. 171, 3, p. 812-29 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GABAergic actions on cholinergic laterodorsal tegmental neurons: Implications for control of behavioral state
Kohlmeier, Kristi Anne & Kristiansen, Uffe, 2009, In: Journal of Neuroscience.Research output: Contribution to journal › Conference abstract in journal › Research
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Pharmacological evidence of functional inhibitory metabotrophic glutamate receptors on mouse arousal-related cholinergic laterodorsal tegmental neurons
Kohlmeier, Kristi Anne, Christensen, M. H., Kristensen, M. P. & Kristiansen, Uffe, 2013, In: Neuropharmacology. 66, p. 99-113Research output: Contribution to journal › Journal article › Research › peer-review
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GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology
Krall, J., Balle, T., Krogsgaard-Larsen, N., Sørensen, T. E., Krogsgaard-Larsen, Povl, Kristiansen, Uffe & Frølund, Bente, 2015, Diversity and functions of GABA receptors: A tribute to Hanns Möhler, Part A. Vol. 72. p. 201-27 27 p. (Advances in Pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Hydroxylated analogues of 5-aminovaleric acid as 4-aminobutyric acidB receptor antagonists: stereostructure-activity relationships
Kristiansen, Uffe, bjl587, bjl587, Herdeis, C., Lund, Trine Meldgaard, Nielsen, Birgitte, Hansen, J. J., Falch, E., Hjeds, H. & Krogsgaard-Larsen, Povl, Mar 1992, In: Journal of Neurochemistry. 58, 3, p. 1150-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benzodiazepine and barbiturate ligands modulate responses of cultured hippocampal neurones to the GABA(A) receptor partial agonist, 4-PIOL
Kristiansen, Uffe & Lambert, J. D. C., 1996, In: Neuropharmacology. 35, 9-10, p. 1181-1191 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Electrophysiological studies of the GABAA receptor ligand, 4‐PIOL, on cultured hippocampal neurones
Kristiansen, Uffe, Lambert, J. D. C., Falch, E. & Krogsgaard-Larsen, Povl, Sep 1991, In: British Journal of Pharmacology. 104, 1, p. 85-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The low efficacy γ-aminobutyric acid type A agonist 5-(4- piperidyl)isoxazol-3-ol opens brief Cl- channels in embryonic rat olfactory bulb neurons
Kristiansen, Uffe, Barker, J. L. & Serafini, R., 1995, In: Molecular Pharmacology. 48, 2, p. 268-279 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand Structural Specificity of GABAA Receptors in Guinea Pig Ileum
Kristiansen, Uffe & Fjalland, B., May 1991, In: Pharmacology & Toxicology. 68, 5, p. 332-339 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ligands for the GABAA receptor complex
Krogsgaard-Larsen, Povl, Frølund, Bente, Kristiansen, Uffe & Ebert, B., 1 Jan 2001, Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology. CRC Press, p. 236-274 39 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
ID: 985515
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Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)
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181
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Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors
Research output: Contribution to journal › Journal article › Research › peer-review
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171
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Astrocytic GABA transporter activity modulates excitatory neurotransmission
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