Søren Brøgger Christensen

Søren Brøgger Christensen

Professor emeritus, Professor, emeritus

Member of:

    ORCID: 0000-0002-5773-6874

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    1. Published

      Accelerating the domestication of new crops: feasibility and approaches

      Østerberg, J. T., Xiang, Wen, Olsen, L. I., Edenbrandt, A. K., Vedel, S. E., Christiansen, Andreas, Landes, X., Andersen, M. M., Pagh-Rasmussen, Peter, Sandøe, Peter, Nielsen, J., Christensen, Søren Brøgger, Thorsen, Bo Jellesmark, Kappel, Klemens, Gamborg, Christian & Palmgren, Michael, 2017, In: Trends in Plant Science. 22, 5, p. 373-384 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Psychotropic constituents of Mentha aquatica L.

      van Staden, J., Stafford, G. I., Almqvist, J. P., Vangsøe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A. & Jäger, A. K., 2007.

      Research output: Contribution to conference › Poster › Research

    3. Published

      Phorbol Rearrangements

      Zimmermann, T., Franzyk, Henrik & Christensen, Søren Brøgger, 28 Sep 2018, In: Journal of Natural Products. 81, 9, p. 2134-2137 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

      Zimmermann, T., Christensen, Søren Brøgger & Franzyk, Henrik, 15 Jun 2018, In: Molecules. 23, 6, 13 p., 1463.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-O-(12-Aminododecanoyl)- 8-O-Debutanoylthapsigargin

      Zimmermann, T., Drasar, P., Rempelova, S., Christensen, Søren Brøgger, Khripach, V. & Jurasek, M., 2020, In: Biomolecules. 10, 11 p., 1640.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed

      Ziegler, H. L., Hansen, Harald S., Stærk, Dan, Christensen, Søren Brøgger, Hägerstrand, H. & Jaroszewski, J. W., 2004, In: Antimicrobial Agents and Chemotherapy. 48, p. 4067-4071

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria

      Zhai, L., Blom, J., Chen, M., Christensen, Søren Brøgger & Kharazmi, A., 1995, In: Antimicrobial Agents and Chemotherapy. 39, 12, p. 2742-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The antileishmanial activity of novel oxygenated chalcones and their mechanism of action

      Zhai, L., Chen, M., Blom, J., Theander, Thor Grundtvig, Christensen, Søren Brøgger & Kharazmi, A., 1999, In: Journal of Antimicrobial Chemotherapy. 43, 6, p. 793-803 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs

      Winther, A. L., Liu, Huizhen, Sonntag, Y., Olesen, C., le Maire, M., Søhoel, H., Olsen, C. E., Christensen, Søren Brøgger, Nissen, P. & Møller, J. V., 2010, In: Journal of Biological Chemistry. 285, 37, p. 28883-28892

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain

      Verma, A., Hirsch, D. J., Hanley, M. R., Thastrup, O., Christensen, Søren Brøgger & Snyder, S. H., 1990, In: Biochemical and Biophysical Research Communications. 172, 2, p. 811-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases

      Vandecaetsbeek, I., Christensen, Søren Brøgger, Liu, Huizhen, van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P., 1 May 2011, In: BBA General Subjects. 1813, 5, p. 1118-1127

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Psychotropic constituents of Mentha aquatica L.

      Van Staden, J., Stafford, G. ,. I., Almqvist, J. P., Vangsoe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A. & Jäger, A., Aug 2007, In: Planta Medica. 73, 9, p. 928-929

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)

      Tung, T., Dao, T. T., Junyent, M. G., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 8 Jan 2018, In: ChemMedChem. 13, 1, 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      LEGO-inspired drug design: Discovery of novel fungal Plasma membrane H+-ATPase (Pma1) inhibitors from small molecule libraries: An introduction of HFSA-SBS_DOS-RD strategy in drug discovery.

      Tung, T. T., Dao, T. T., Palmgren, M. B., Fuglsang, A. T., Christensen, Søren Brøgger & Nielsen, J., 2 Apr 2017.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    15. Published

      A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases

      Treiman, M., Caspersen, C. & Christensen, Søren Brøgger, 1 Jan 1998, In: Trends in Pharmacological Sciences. 19, 4, p. 131-135 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      19a-hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum

      Traore, M., Ziegler, H. L., Olsen, C. E., Hassanata, M., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2009, In: Natural Product Research. 23, 12, p. 1108-1111 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      A new oxygenated ursane derivative from Canthium multiflorum

      Traore, M., Jaroszewski, J. W., Olsen, C. E., Ouédraogo, J. B., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2008, In: Planta Medica. 74, 5, p. 560-562 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Cytotoxic kurubasch aldehyde from Trichilia emetica

      Traore, M., Zhai, L., Chen, M., Olsen, C. E., Odile, N., Pierres, G. I., Bosco, O. J., Robert, G. T. & Christensen, Søren Brøgger, 2007, In: Natural Product Reports. 21, 1, p. 13-17

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Molluscicidal saponins from a Zimbabwean strain of Phytolacca dodecandra

      Thiilborg, S. T., Christensen, Søren Brøgger, Cornett, Claus, Olsen, C. E. & Lemmich, E., 1994, In: Phytochemistry. 36, 3, p. 753-759 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Molluscicidal saponins from Phytolacca dodecandra

      Thiilborg, S. T., Christensen, Søren Brøgger, Cornett, Claus, Olsen, C. E. & Lemmich, E., 1993, In: Phytochemistry. 32, 5, p. 1167-1171 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Thapsigargin: a novel molecular probe for studying intracellular calcium release and storage

      Thastrup, Ole, Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drøbak, B. K., Bjerrum, P. J., Christensen, Søren Brøgger & Hanley, M. R., 1994, In: Agents and Actions. 43, 3-4, p. 187-93 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

      Thastrup, Ole, Linnebjerg, H., Bjerrum, P. J., Knudsen, J. B. & Christensen, Søren Brøgger, 1987, In: BBA General Subjects. 927, 1, p. 65-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds

      Thanh Tung, T., Christensen, Søren Brøgger & Nielsen, J., 25 Oct 2017, In: Chemistry - A European Journal. 2 p.

      Research output: Contribution to journal › Journal article › Communication

    24. Published

      LEGO-inspired drug design: unveiling a class of Benzo[d]thiazoles containing a 3,4-Dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors

      Thanh Tung, T., Dao, T. T., Grifell Junyent, M., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 2018, In: ChemMedChem. 13, 1, 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors

      Thanh Tung, T., Jakobsen, Tim Holm, Dao, T. T., Fuglsang, Anja Thoe, Givskov, Michael, Christensen, Søren Brøgger & Nielsen, J., 2017, In: European Journal of Medicinal Chemistry. 126, p. 1011-1020 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds

      Thanh Tung, T., Christensen, Søren Brøgger & Nielsen, J., 11 Oct 2017, In: Chemistry: A European Journal. 23, p. 18125-18128

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

      Tarvainen, I., Zimmermann, T., Heinonen, P., Jäntti, M. H., Yli-Kauhaluoma, J., Talman, V., Franzyk, Henrik, Tuominen, R. K. & Christensen, Søren Brøgger, 2020, In: A C S Medicinal Chemistry Letters. 11, 5, p. 671-677 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity

      Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In: Biochemical Systematics and Ecology. 39, 2, p. 153-155

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death

      Szalai, P., Parys, J. B., Bultynckb, G., Christensen, Søren Brøgger, Nissen, P., Møller, J. V. & Engedal, N., Dec 2018, In: Cell Calcium. 76, p. 48-61 14 p., https://doi.org/10.1016/j.ceca.2018.09.005.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)

      Stafford, G. I., Birer, C., Larsen, Birger Brodin, Christensen, Søren Brøgger, Eriksson, A. H., Jäger, A. & Rønsted, Nina, Sep 2013, In: South African Journal of Botany. 88, p. 101-106 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Mild psychoactive constituents of Mentha aquatica L.

      Stafford, G. I., Almqvist, J. P., Vangsøe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A., Jäger, A. K. & van Staden, J., 2008, In: South African Journal of Botany. 2, p. 389

      Research output: Contribution to journal › Conference abstract in journal › Research

    32. Published

      NEW PROAZULENE GUAIANOLIDES FROM THAPSIA-VILLOSA

      Smitt, U. W., Cornett, Claus, Andersen, A., Christensen, Søren Brøgger & Avato, P., 1990, In: Journal of Natural Products. 53, 6, p. 1479-1484 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Nortrilobolide, a new potent guaianolide secretagogue from Thapsia garganica

      Smitt, U. W. & Christensen, Søren Brøgger, 25 Apr 1991, In: Planta Medica. 57, 2, p. 196-197 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      HYDROINDENE SESQUITERPENES FROM THAPSIA-VILLOSA

      Smitt, U. W., Cornett, Claus, Norup, E. & Christensen, Søren Brøgger, 1990, In: Phytochemistry. 29, 3, p. 873-875 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Carroll rearrangement to construct the norneolignan skeleton

      Skytte, D. M., Rasmussen, H. B. & Christensen, Søren Brøgger, 2008, In: Natural Product Research. 22, 2, p. 116-123

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase

      Skytte, D. M., Møller, J. V., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M., Olsen, C. E. & Christensen, Søren Brøgger, 2010, In: Bioorganic & Medicinal Chemistry. 18, 15, p. 5634-5646 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida

      Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars, Kharazmi, A., Nkrumah, F. K. & Christensen, Søren Brøgger, 1999, In: Planta Medica. 65, 3, p. 259-61 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Alkamides from Phyllanthus fraternus

      Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase

      Singh, P., Mhaka, A. M., Christensen, Søren Brøgger, Gray, J. J., Denmeade, S. R. & Isaacs, J. T., 21 Apr 2005, In: Journal of Medicinal Chemistry. 48, 8, p. 3005-3014 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Evaluation of Medicinal Plants from Chile

      Simonsen, H. T., Guzman, A., Adsersen, A., Christensen, Søren Brøgger & Mølgaard, Per, 2008.

      Research output: Contribution to conference › Conference abstract for conference › Research

    41. Published

      Guaianolide Sesquiterpenoids: Pharmacology and biosynthesis

      Simonsen, H. T., Weitzel, C. & Christensen, Søren Brøgger, 2013, Natural products: phytochemistry, botany and metabolism of alkaloids, phenolics and terpenes. Ramawat, K. G. & Mérillon, J-M. (eds.). Springer, p. 3069-3098 30 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    42. Published

      S-petasin and butterbur lactones dilate vessels through blockage of voltage gated calcium channels and block DNA synthesis

      Sheykhzade, Majid, Smajilovic, S., Issa, A., Haunsø, Stig, Christensen, Søren Brøgger & Tfelt-Hansen, J., 28 Sep 2008, In: European Journal of Pharmacology. 593, 1-3, p. 79-86

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response

      Sehgal, P., Szalai, P., Praetorius, H. A., Nissen, Poul, Christensen, Søren Brøgger, Engedal, N. & Møller, J. V., 2 Oct 2017, In: Journal of Biological Chemistry. 292, 48, p. 19656-19673

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

      Scharff, O., Foder, B., Thastrup, Ole, Hofmann, B., Møller, J., Ryder, L. P., Jacobsen, K. D., Langhoff, E., Dickmeiss, E. & Christensen, Søren Brøgger, 1988, In: BBA General Subjects. 972, 3, p. 257-64 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)

      Saaby, Lasse, Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In: Planta Medica. 76, 12, p. 1171

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    46. Published

      Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)

      Saaby, Lasse, Jäger, A. K., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Feb 2011, In: Phytotherapy Research. 25, 2, p. 195-201

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Planternes slægtskab som skattekort til nye lægemidler

      Rønsted, Nina, Larsen, Birger Brodin, Christensen, Søren Brøgger, Eriksson, A. H. & Jäger, A. K., Dec 2010, In: Lægemiddelforskning. 2010, p. 19-21

      Research output: Contribution to journal › Journal article › Communication

    48. Published

      Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae

      Rønsted, Nina, Symonds, M. R. E., Birkholm, T., Christensen, Søren Brøgger, Meerow, A. W., Schmidt, M. M., Mølgaard, Per, Petersen, G., Rasmussen, N., van Staden, J., Stafford, G. I. & Jäger, A., 14 Sep 2012, In: BMC Evolutionary Biology. 12, 12 p., 182.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa

      Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, Søren Brøgger, Søhoel, H. & Massanet, G. M., 2010, In: Planta Medica. 76, 3, p. 284-290

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

      Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, Karla Andrea, Christensen, Søren Brøgger, Nielsen, C. & Eriksson, M., 2006, In: Journal of Natural Products. 69, 11, p. 1566-71 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Thapsigargine and thapsigargicine, two new histamine liberators from Thapsia garganica L

      Rasmussen, U., Christensen, Søren Brøgger & Sandberg, F., 1 Jan 1978, In: Acta Pharmaceutica Suecica. 15, 2, p. 133-140 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Structure and biological activity of sesquiterpene lactones from Thapsia species and of analogue derivatives

      Rasmussen, U., Christensen, Søren Brøgger & Patkar, S. A., 1 Jan 1982, In: Planta Medica. 45, 3, p. P23

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Phytochemical and pharmacological investigations of the genus Thapsia (Apiaceae)

      Rasmussen, U., Christensen, Søren Brøgger & Sandberg, F., 1 Jan 1978, In: PLANTA MED.. 33, 3, p. 301-302 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Phytochemistry of the genus Thapsia

      Rasmussen, U., Christensen, Søren Brøgger & Sandberg, F., 1 Jan 1981, In: Planta Medica. 43, 4, p. 336-341 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa

      Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P. & Karazmi, A., 22 Jun 2000, In: Planta Medica. 66, 4, p. 396-398 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Absolute configuration and antiprotozoal activity of minquartynoic acid

      Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P., Kharazmi, A. & Huansi, A. G., 2000, In: Journal of Natural Products. 63, 9, p. 1295-6 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Isolation of tow high-polar fractions from 'Banlangen', root of isatis tinctoria L. and its activity

      Qin, Q., He, H. P., Christensen, Søren Brøgger, Rasmussen, H. B., Kharazmi, A. & Chen, M., 1 Jan 2001, In: Chinese Pharmacological Bulletin. 17, 6, p. 714-715 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase

      Paulsen, E. S., Villadsen, J., Tenori, E., Liu, Huizhen, Bonde, D. F., Lie, M. A., Bublitz, M., Olesen, C. L., Autzen, Henriette Elisabeth, Dach, I., Sehgal, P., Nissen, P., Møller, J., Schiøtt, B. & Christensen, Søren Brøgger, 9 May 2013, In: Journal of Medicinal Chemistry. 56, 9, p. 3609-19 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Bioassay-guided identification and isolation of anticancer components in Hypholoma fasciculare extract

      Pang, W. S. K., Chen, M., Zhai, L. & Christensen, Søren Brøgger, 2008.

      Research output: Contribution to conference › Poster › Research

    60. Published

      Are we ready for back-to-nature crop breeding?

      Palmgren, Michael, Edenbrandt, A. K., Vedel, S. E., Andersen, M. M., Landes, X., Østerberg, J. T., Falhof, J., Olsen, L. I., Christensen, Søren Brøgger, Sandøe, Peter, Gamborg, Christian, Kappel, Klemens, Thorsen, Bo Jellesmark & Pagh-Rasmussen, Peter, 2015, In: Trends in Plant Science. 20, 3, p. 155-164 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Isolation of the MAO-inhibitor naringenin from Mentha aquatica L

      Olsen, H. T., Stafford, G. I., van Staden, J., Christensen, Søren Brøgger & Jäger, A. K., 2008, In: Journal of Ethnopharmacology. 117, 3, p. 500-502

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Two new antiprotozoal 5-methylcoumarins from Vernonia brachycalyx

      Oketch-Rabah, H. A., Lemmich, E., Dossaji, S. F., Theander, Thor Grundtvig, Olsen, C. E., Cornett, Claus, Kharazmi, A. & Christensen, Søren Brøgger, 1997, In: Journal of Natural Products. 60, 5, p. 458-61 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx

      Oketch-Rabah, H. A., Christensen, Søren Brøgger, Frydenvang, Karla Andrea, Dossaji, S. F., Theander, Thor Grundtvig, Cornett, Claus, Watkins, W. M., Kharazmi, A. & Lemmich, E., 1998, In: Planta Medica. 64, 6, p. 559-62 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Analysis of the stimulative effect of thapsigargin, a non‐TPA‐type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages

      Ohuchi, K., Sugawara, T., Watanabe, M., Hirasawa, N., Tsurufuji, S., Fujiki, H., Christensen, Søren Brøgger & Sugimura, T., Jul 1988, In: British Journal of Pharmacology. 94, 3, p. 917-923 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter

      Ohuchi, K., Sugawara, T., Watanabe, M., Hirasawa, N., Tsurufuji, S., Fujiki, H., Sugimura, T. & Christensen, Søren Brøgger, 1 Jun 1987, In: Journal of Cancer Research and Clinical Oncology. 113, 4, p. 319-324 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Synergistic stimulation of histamine release from rat peritoneal mast cells by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters

      Ohuchi, K., Hirasawa, N., Takahashi, C., Watanabe, M., Tsurufuji, S., Fujiki, H., Suganuma, M., Hakii, H., Sugimura, T. & Christensen, Søren Brøgger, 16 Jun 1986, In: BBA - Molecular Cell Research. 887, 1, p. 94-99 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      The potencies of thapsigargin and analogues as activators of rat peritoneal mast cells

      Norup, E., Smitt, U. W. & Christensen, Søren Brøgger, 1 Jan 1986, In: Planta Medica. NO. 4, p. 251-255 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Structure-activity relationships of thapsigargin

      Nielsen, S. F., Andersen, A., Olsen, C. E., Treimann, M., Thastrup, Ole & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A678-A679

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Modifications of the alpha,beta-double bond in chalcones only marginally affect the antiprotozoal activities

      Nielsen, S. F., Kharazmi, A. & Christensen, Søren Brøgger, 1998, In: Bioorganic & Medicinal Chemistry. 6, 7, p. 937-45 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Synthesis of antiparasitic licorice chalcones

      Nielsen, S. F., Chen, M., Theander, Thor Grundtvig, Kharazmi, A. & Christensen, Søren Brøgger, 1995, In: Bioorganic & Medicinal Chemistry Letters. 5, p. 449-452 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Structure-activity relationships of analogues of thapsigargin modified at O-11 and O-12

      Nielsen, S. F., Thastrup, Ole, Pedersen, R., Olsen, C. E. & Christensen, Søren Brøgger, 1995, In: Journal of Medicinal Chemistry. 38, 2, p. 272-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Perturbing dissimilar biomolecular targets from natural product scaffolds and focused chemical decoration.

      Nielsen, J., Tung, T. T., Tim, H. J., Trong Tuan, D., Anja T., F., Michael, G. & Christensen, Søren Brøgger, 2 Apr 2017. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    73. Published

      Direct difluoromethylation of heterocycles using difluoroacetic acid

      Nielsen, J., Truong Thanh Tung & Christensen, Søren Brøgger, 19 Aug 2018.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    74. Published

      Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds - Scope, Limitations and Perspectives

      Nielsen, J., Christensen, Søren Brøgger & Tung, T. T., Dec 2018, In: Synthesis. 50, 23, p. A193-A196 4 p.

      Research output: Contribution to journal › Conference article › Research › peer-review

    75. Published

      Proacaciberin, A cyanogenic glycoside from Acacia sieberiana var. Woodii

      Nartey, F., Brimer, L. & Christensen, Søren Brøgger, 1981, In: Phytochemistry. 20, 6, p. 1311-1314 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A

      Nadelmann, L., Tjornelund, J., Hansen, S. H., Cornett, Claus, Sidelmann, U. G., Braumann, U., Christensen, E. & Christensen, Søren Brøgger, 1997, In: Xenobiotica. 27, 7, p. 667-680 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      A new sesquiterpene from laserpitium latifolium

      Moldt, P., Smitt, U. W. & Christensen, Søren Brøgger, 1 Sep 1987, In: Journal of Natural Products. 50, 5, p. 974-975 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Dimethyl sulfoxide decreases the fluorescence yield of the reaction between histamine and ortho-phthalaldehyde and may influence histamine release

      Moldt, P., Andersen, W. K. & Christensen, Søren Brøgger, 1 Jun 1988, In: Agents and Actions. 24, 1-2, p. 35-39 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      6-O-Methylkrigeine, a new Amaryllidaceae alkaloid from Nerine huttoniae Schönland

      Molander, M., Christensen, Søren Brøgger, Jaeger, A. K., Olsen, C. E. & Rønsted, Nina, 2012, In: Natural Product Research. 26, 1, p. 56-60 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Comparison of the Effects of Thapsigargin and BAY K 8644 on Spontaneous Mechanical Activity in Rat Portal Vein and Contractile Responses of Rat Cardiac Muscle

      Mikkelsen, E. O., Poulsen, S. H. & Christensen, Søren Brøgger, Feb 1992, In: Pharmacology & Toxicology. 70, 2, p. 152-156 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Effects of thapsigargin in isolated rat thoracic aorta

      Mikkelsen, E. O., Thastrup, Ole & Christensen, Søren Brøgger, 1988, In: Pharmacology & Toxicology. 62, 1, p. 7-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump

      Mahmmoud, Y. A. & Christensen, Søren Brøgger, Oct 2011, In: BBA General Subjects. 1808, 10, p. 2413-2420

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Calcium entry in Xenopus oocytes: effects of inositol trisphosphate, thapsigargin and DMSO

      Lupu-Meiri, M., Beit-Or, A., Christensen, Søren Brøgger & Oron, Y., Feb 1993, In: Cell Calcium. 14, 2, p. 101-110 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Iminolactones from Schizophyllum commune

      Liu, X., Frydenvang, Karla Andrea, Liu, H., Zhai, L., Chen, M., Olsen, C. E. & Christensen, Søren Brøgger, 2015, In: Journal of Natural Products. 78, 5, p. 1165-1168 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica

      Liu, Huizhen, Jensen, K. G., Tran, L. M., Chen, M., Zhai, L., Olsen, C. E., Søhoel, H., Denmeade, S. R., Issacs, J. T. & Christensen, Søren Brøgger, 2006, In: Phytochemistry. 67, 24, p. 2651-2658 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components

      Lindner, P., Christensen, Søren Brøgger, Nissen, Poul, Moller, J. V. & Engedal, N., 2020, In: Cell Communication and Signaling. 18, 23 p., 12.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Synthesis of the thapsigargins

      Ley, S. V., Antonello, A., Balskus, E. P., Booth, D. T., Christensen, Søren Brøgger, Cleator, E., Gold, H., Högenauer, K., Hünger, U., Myers, R. M., Oliver, S. F., Simic, O., Smith, M. D., Søhoel, H. & Woolford, A. J. A., 17 Aug 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 33, p. 12073-12078 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Novel Guaiane Esters from Thapsia villosa

      Lemmich, E., Smitt, U. W., Kastrup, Jette Sandholm Jensen & Christensen, Søren Brøgger, 1991, In: Phytochemistry. 30, p. 2987-2990 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Exciton Coupling in Circular Dichroic Spectroscopy as a Tool for Establishing the Absolute Configuration of alpha,beta-Unsaturated Esters of Allylic Alcohols

      Lauridsen, A., Cornett, Claus & Christensen, Søren Brøgger, 1991, In: Acta Chemica Scandinavica. Supplementum. 45, 1, p. 56-62 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Syntheses of 11-hydroxylated guaianolides

      Lauridsen, A., Cornett, Claus, Vulpius, T., Moldt, P. & Christensen, Søren Brøgger, 1996, In: Acta Chemica Scandinavica. Supplementum. 50, 2, p. 150-157 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro

      Larsen, Erik, Kharazmi, A., Christensen, L. P. & Christensen, Søren Brøgger, 1 Jul 2003, In: Journal of Natural Products. 66, 7, p. 994-995 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Identification of natural products using HPLC-SPE combined with CapNMR

      Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In: Analytical Chemistry. 79, 2, p. 727-735

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis

      Kvist, L. P., Christensen, Søren Brøgger, Rasmussen, H. B., Mejia, K. & Gonzalez, Ana Valeria, 19 Jul 2006, In: Journal of Ethnopharmacology. 106, 3, p. 390-402 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Organic hydroxylamine derivatives. VIII. Structural analogues of GABA of the isoxazole enol betaine type. Synthesis of 5,6,7,8 tetrahydro 4H isoxazolo[3,4 d]azepin 3 ol zwitterion and some derivatives

      Krogsgaard-Larsen, Povl, Hjeds, H. & Christensen, Søren Brøgger, 1 Jan 1973, In: Acta Chemica Scandinavica. 27, 9, p. 3251-3258 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Organic hydroxylamine derivatives. VII. Isoxazolin 5 ones. An investigation of a reaction sequence previously stated to give 3 hydroxyisoxazoles

      Krogsgaard-Larsen, Povl, Christensen, Søren Brøgger & Hjeds, H., 1 Jan 1973, In: Acta Chemica Scandinavica. 27, 8, p. 2802-2812 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Muscimol analogues. I. Syntheses of 4- and 8-aminocycloheptenol[1,2 d]isoxazol-3-ols and 4-(3-aminopropyl)-5-methyl-3-isoxazolol

      Krogsgaard-Larsen, Povl, Natova, L. & Christensen, Søren Brøgger, 1 Jan 1977, In: ACTA CHEM. SCAND.. B31, 7, p. 577-583 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Discovery of oxygenated chalcoes as novel antimalarial agents

      Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Discovery of oxygentade chalcones as novel antimalarial agents

      Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell.

      Khalid, S. A., Friedrichsen, G. M., Christensen, Søren Brøgger, El Tahir, A. & Satti, G. M., 29 Jan 2007, In: ARKIVOC. 2007, 9, p. 129-134 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell.

      Khalid, S. A., Friedrichsen, G. M., Christensen, Søren Brøgger, El Tahir, A. & Satti, G. M., 2007, In: Arkivoc. ix, p. 129-134

      Research output: Contribution to journal › Journal article › Research › peer-review

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